Evaluation of an epithelial plasticity biomarker panel in men with localized prostate cancer
نویسندگان
چکیده
منابع مشابه
Evaluation of an Epithelial Plasticity (EP) Biomarker Panel in Men with Localized Prostate Cancer
Background—Given the potential importance of epithelial plasticity (EP) to cancer metastasis, we sought to investigate biomarkers related to EP in men with localized prostate cancer (PC) for the association with time to PSA recurrence and other clinical outcomes after surgery. Methods—Men with localized PC treated with radical prostatectomy at the Durham VA medical center and whose prostatectom...
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Prognostic biomarkers are needed to distinguish patients with clinically localized prostate cancer (PCa) who are at high risk of metastatic progression. The tumor transcriptome may reveal its aggressiveness potential and have utility for predicting adverse patient outcomes. Genomewide gene expression levels were measured in primary tumor samples of 383 patients in a population-based discovery c...
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ژورنال
عنوان ژورنال: Prostate Cancer and Prostatic Diseases
سال: 2015
ISSN: 1365-7852,1476-5608
DOI: 10.1038/pcan.2015.46